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How does an Infliximab infusion for Crohn’s disease work?
Infliximab works by blocking the action of a protein in your body called TNF-alpha (tumour necrosis factor-alpha). The body's own immune system makes TNF-alpha and patients who have diseases like Crohn's have an excess of TNF-alpha in tissue. This causes the immune system to attack normal healthy parts of the body, like the bowel and cause disease. Infliximab is designed to block TNF-alpha, decreasing inflammation and damage.